Side effects to ferrous sulphates are common1
Your own clinical experience may tell you that important iron medications may often go unused because of gastrointestinal side effects. Let’s take a look at the adverse events recorded in a recent clinical trial to see if your clinical experience matches these findings.
In an exploratory, open-label, randomized, controlled, multicenter study undertaken in pregnant women with iron-deficiency anaemia. Patients were randomized 1:1 to Maltofer® (oral iron(III) polymaltose complex) or ferrous sulphate (each 100 mg iron twice daily) for 90 days.
The primary endpoint, change in haemoglobin from baseline to days 60 and 90, did not differ significantly between treatment groups. The Maltofer® group showed a 21.6 g/L improvement in haemoglobin versus 19.3g/L for the ferrous sulphate group. However, adverse events were significantly less frequent in the Maltofer® group, occurring in 29.3% of patients, compared with 56.4% of patients in the ferrous sulphate group (p = 0.015)